Thermo Fisher Scientific Histone H1.2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

ChIP assay (ChIP)

• Tested Dilution: 0.5 µg

Product Specifications

Product Specific Information

• Peptide Sequence: ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS
• Sequence Homology:
  Cow: 86%
  Dog: 86%
  Guinea Pig: 93%
  Horse: 86%
  Human: 100%
  Mouse: 86%
  Rabbit: 85%
  Rat: 86%

Target Information

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is located in the large histone gene cluster on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.