Thermo Fisher Scientific CPS1 Monoclonal Antibody (5F5)
CPS1 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ELISA 등 다양한 응용 가능. 인간 시료 반응성, BSA 결합 합성 펩타이드 면역원 사용. 액상 형태, PBS buffer, 무보존제, -20°C 보관.
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Thermo Fisher Scientific CPS1 Monoclonal Antibody (5F5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.75 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F5 |
| Immunogen | A synthetic peptide (conjugated with BSA) corresponding to internal region of human CPS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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