Thermo Fisher Scientific Kir6.2 (KCNJ11) Polyclonal Antibody
Kir6.2(KCNJ11) 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 1 mg/mL 농도의 액상 형태로, Protein A 정제 및 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Kir6.2 (amino acids 301–390) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This receptor is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the voltage range of channel opening shifts to more positive voltages. The inward rectification is mainly due to blockage of outward current by internal magnesium and can be inhibited by extracellular barium. It is a subunit of ATP-sensitive potassium channels (KATP) and can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore, while ABCC9 is required for activation and regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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