Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI1E1), TrueMAB
인간 C17orf37 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 트레할로스 함유 PBS 버퍼, 보존제 무첨가. 유방암 관련 바이오마커 연구용.
- 카탈로그번호
- CF504613
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E1 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended.
(Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882)
Target Information
The ERBB2 (neu/HER2) oncogene is a well-established predictor of patient outcome and therapy response in breast cancer.
C35 (C17orf37) is a novel tumor biomarker highly expressed in breast cancer.
The C35 gene is located on chromosome 17q12, 505 nucleotides from the 3′ end of the ERBB2 oncogene, the target for trastuzumab (Herceptin) therapy.
The genes encoding C35 and ERBB2 are arranged tail-to-tail.
The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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