Thermo Fisher Scientific Phospho-Histone H3 (Tyr41) Polyclonal Antibody
Human Histone H3 (Tyr41) 인산화 부위를 인식하는 폴리클로날 항체로, ICC/IF 및 ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품. PBS/glycerol 버퍼에 보존되어 안정적이며, 연구용으로 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:10–1:100
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from Human Histone H3.1 protein (37–48aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2915031 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can directly alter chromatin structure or facilitate binding of transcription factors. The N-terminal tail of histone H3 undergoes several modifications such as methylation, acetylation, and phosphorylation, influencing key cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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