Thermo Fisher Scientific CRYM Polyclonal Antibody
Human CRYM 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, IHC(P), ICC/IF 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CRYM. Recombinant protein control fragment (Product #RP-105834) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2663317 |
Product Specific Information
Immunogen sequence:
YEIFTEQFSFK EVRIWNRTKE NAEKFADTVQ GEVRVCSSVQ EAVAGADVII TVTLATEPIL FGEWVKPGAH INAVGASRPD WRE
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 92%
Target Information
Crystallins are divided into two classes: taxon-specific and ubiquitous.
- Taxon-specific (phylogenetically restricted) crystallins are expressed in specific tissues or species.
- Ubiquitous crystallins are the major proteins of vertebrate eye lens, maintaining transparency and refractive index.
The CRYM gene encodes a taxon-specific crystallin protein that binds NADPH and shows sequence similarity to bacterial ornithine cyclodeaminases. Unlike structural lens proteins, it binds thyroid hormone, potentially playing a regulatory or developmental role. Multiple alternatively spliced transcript variants have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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