Thermo Fisher Scientific GPR125 Polyclonal Antibody
Human GPR125 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPR125. Recombinant protein control fragment (Product #RP-89573). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642162 |
Product Specific Information
Immunogen sequence:
DIFRGLTNLV RLNLSGNLFS SLSQGTFDYL ASLRSLEFQT EYLLCDCNIL WMHRWVKEKN ITVRDTRCVY PKSLQAQPVT GVKQELLTCD PPLELPSFYM TPSHRQVVFE GDSLPFQCMA SYIDQDMQVL WYQDGRI
- Highest antigen sequence identity to orthologs:
- Mouse: 97%
- Rat: 96%
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, form a superfamily of proteins involved in various stimulus-response pathways.
GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily.
It is a novel orphan adhesion-type receptor with five leucine-rich repeats (LRR), an immunoglobulin (Ig) domain, and a GPS domain.
GPR125 may play a role in choroidal and hippocampal responses to brain injury and may serve as a marker for spermatogonial stem cells.
Four isoforms of GPR125 exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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