Thermo Fisher Scientific Periplakin Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Periplakin 단백질 검출용 Rabbit Polyclonal Antibody. Western blot과 IHC(Paraffin)에 적합하며, 항원 친화 크로마토그래피로 정제됨. 고농도 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 28–305 of Human Periplakin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548405 |
Product Specific Information
- Recommended positive controls: U87-MG
- Predicted reactivity: Mouse (91%), Rat (91%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes.
The N-terminal domain interacts with the plasma membrane and the C-terminus interacts with intermediate filaments.
Through its rod domain, this protein forms complexes with envoplakin and may serve as a link between the cornified envelope, desmosomes, and intermediate filaments.
AKT1/PKB, a protein kinase mediating cell growth and survival signaling, is reported to interact with this protein, suggesting a possible role as a localization signal in AKT1-mediated signaling.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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