Thermo Fisher Scientific GNPDA1 Monoclonal Antibody (237CT2.5.2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:1,000

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

237CT2.5.2

Immunogen

GNPDA1 recombinant protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897449

Target Information

GNPDA1 is a 289 amino acid cytoplasmic protein belonging to the glucosamine/ galactosamine-6-phosphate isomerase family. It is one of the two mammalian glucosamine-6-phosphate deaminase enzymes. GNPDA1 is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium with an aldo/keto isomerization and an amination/deamination. GNPDA1 may trigger calcium oscillations in mammalian eggs at fertilization which in turn serve as an important factor for egg development and early embryo development. It is a homohexamer, ubiquitously expressed in most of human tissues with high expression in testis, ovary, placenta, and heart and also in various cell lines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.