Thermo Fisher Scientific CDC42BPA Monoclonal Antibody (OTI12C12), TrueMAB
CDC42BPA 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot에 적합하며 Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며 PBS 및 트레할로오스 완충액 포함. 연구용으로 세포골격 조절 관련 연구에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1419–1638 of human CDC42BPA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
CDC42BPA (MRCKA) is a serine/threonine kinase involved in actin cytoskeleton assembly and organization.
It contains three coiled-coil domains and an N-terminal region that mediate intermolecular interactions leading to MRCK alpha multimerization.
Transautophosphorylation regulates MRCK alpha catalytic activity.
Binding of phorbol esters releases autoinhibition, enabling N-terminal dimerization and kinase activation.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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