Thermo Fisher Scientific p400 Polyclonal Antibody
인간 p400 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태. PBS 완충액(40% glycerol, 0.02% sodium azide) 보존. 연구용 전용 제품.
- 카탈로그번호
- PA553475
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human p400. Recombinant protein control fragment (Product # RP-91695) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645144 |
Product Specific Information
Immunogen sequence:
DDEVDDEEET IEEEEANEGV VDHQTELSNL AKEAELPLLD LMKLYEGAFL PSSQWPRPKP DGEDTSGEED ADDCPGDRES RKDLVLIDSL FIMDQFKAAE RMNIGKPNAK DIADVTAVAE AILPKGSARV TTSVKFNAPS L
Highest antigen sequence identity:
- Mouse: 82%
- Rat: 84%
Target Information
Component of the NuA4 histone acetyltransferase complex, involved in transcriptional activation of select genes through acetylation of nucleosomal histones H4 and H2A. This modification alters nucleosome–DNA interactions and promotes interaction with transcription-regulating proteins. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities are contributed by RUVBL1 and RUVBL2 association with EP400. May regulate ZNF42 transcription activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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