
Thermo Fisher Scientific 5HT2A Receptor/SR-2A Polyclonal Antibody
5HT2A Receptor/SR-2A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Protein A 정제, 1 mg/mL 농도, 연구용 전용.
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Thermo Fisher Scientific 5HT2A Receptor/SR-2A Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human 5HT2A Receptor/SR-2A, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility through G protein-coupled receptors, designated 5-HT or SR receptors. The SR-2 receptor family includes SR-2A, SR-2B, and SR-2C, which activate phospholipase C and release intracellular calcium in response to serotonin.
SR-2A is involved in tracheal smooth muscle contraction, bronchoconstriction, and aldosterone production, and may play roles in psychiatric disorders such as depression and schizophrenia.
SR-2B is expressed in cardiovascular tissues, gut, and brain, contributing to cardiac pathology.
SR-2C is implicated in the effects of atypical antipsychotic drugs.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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