Thermo Fisher Scientific IFITM2 Polyclonal Antibody, MaxPab
IFITM2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. Western blot에 사용 가능하며, IFN 유도 항바이러스 단백질 연구에 적합합니다. 액상 형태로 제공되며, PBS(pH 7.4)에 보관하고 -20°C에서 냉동 보관합니다.
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Thermo Fisher Scientific IFITM2 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IFITM2 (AAH09696.1, 1–132 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MNHIVQTFSP VNSGQPPNYE MLKEEQEVAM LGAPHNPAPP TSTVIHIRSE TSVPDHVVWS LFNTLFMNTC CLGFIAFAYS VKSRDRKMVG DVTGAQAYAS TAKCLNIWAL ILGIFMTILL VIIPVLVVQA QR
Target Information
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis but preventing subsequent viral fusion and release of viral contents into the cytosol.
Active against multiple viruses, including:
- Influenza A virus
- SARS coronavirus (SARS-CoV)
- Marburg virus (MARV)
- Ebola virus (EBOV)
- Dengue virus (DNV)
- West Nile virus (WNV)
- HIV-1
- Vesicular stomatitis virus (VSV)
Can inhibit:
- Influenza virus hemagglutinin protein-mediated viral entry
- MARV and EBOV GP1,2-mediated viral entry
- SARS-CoV S protein-mediated viral entry
- VSV G protein-mediated viral entry
Induces cell cycle arrest and mediates apoptosis by caspase activation in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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