Thermo Fisher Scientific JLP Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells. It functions as a calcium-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, containing three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. The protein also serves as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells. Mutations in this gene are associated with cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants with distinct C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.