Thermo Fisher Scientific KIAA0556 Polyclonal Antibody
KIAA0556 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 친화 크로마토그래피로 정제된 액상 형태입니다. PBS 및 sucrose 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human KIAA0556 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2690644 |
Product Specific Information
This target displays homology in the following species:
- Human: 100%
Target Information
This gene encodes a novel, evolutionarily conserved ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when overexpressed.
A mutation in this gene has been associated with Joubert syndrome, a recessive disorder characterized by a distinctive mid-hindbrain and cerebellar malformation, often associated with broader ciliopathy symptoms. In serum-starvation ciliogenesis assays, fibroblast cells derived from patients with the mutation show reduced numbers of ciliated cells with abnormally long cilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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