Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody
BAIAP2L1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC(P), ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BAIAP2L1 (Product #RP-92593) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping Conditions | Wet ice |
| RRID | AB_2638461 |
Product Specific Information
Immunogen sequence:
LLSFAQGDVI TLLIPEEKDG WLYGEHDVSK ARGWFPSSYT KLLEENETEA VTVPTPSPTP VRSISTVNLS EN
Highest antigen sequence identity to orthologs:
- Mouse: 85%
- Rat: 82%
Target Information
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family are divided into IRSp53-like and MIM-like groups based on the presence or absence of the SH3 domain.
The encoded protein contains a conserved IMD (F-actin bundling domain) at the N-terminus and a canonical SH3 domain near the C-terminus, classifying it as IRSp53-like.
It acts as a substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac, participating in signal transduction pathways that link plasma membrane deformation and actin cytoskeleton remodeling.
Overexpression promotes actin assembly and membrane protrusions in mammalian cells and is essential for potent actin assembly complex formation during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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