Thermo Fisher Scientific ZNF451 Polyclonal Antibody
ZNF451 단백질을 인식하는 Rabbit polyclonal antibody로 인간 시료에 반응합니다. Western blot에 적합하며, SUMO 단백질 결합 및 스트레스 반응 연구에 활용됩니다. 액상 형태로 제공되며, 고순도 친화 크로마토그래피로 정제되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human ZNF451 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688990 |
Product Specific Information
This target displays homology in the following species:
- Cow: 93%
- Dog: 100%
- Horse: 100%
- Human: 100%
- Mouse: 100%
- Pig: 100%
- Rabbit: 87%
- Rat: 100%
Target Information
E3 SUMO-protein ligase with preference for SUMO2 and SUMO3. Facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in SUMO2 modification under DNA damage and proteasome inhibition stress. Required for MCM4 sumoylation. Shows no activity with SUMO1. Preferentially transfers an additional SUMO2 chain onto SUMO2 consensus site Lys-11. Negatively regulates SMAD4-mediated transcriptional activation in TGF-beta signaling and inhibits EP300-mediated histone H3 acetylation at Lys-9. Involved in transcriptional regulation of AR targets. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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