Thermo Fisher Scientific EPO Polyclonal Antibody, MaxPab
Erythropoietin(EPO) 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료와 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS(pH7.4)에 보존제가 포함되지 않은 액상 형태로 제공됩니다.
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Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EPO (NP_000790.2, 1 a.a. ~ 193 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGVHECPAWL WLLLSLLSLP LGLPVLGAPP RLICDSRVLE RYLLEAKEAE NITTGCAEHC SLNENITVPD TKVNFYAWKR MEVGQQAVEV WQGLALLSEA VLRGQALLVN SSQPWEPLQL HVDKAVSGLR SLTTLLRALG AQKEAISPPD AASAAPLRTI TADTFRKLFR VYSNFLRGKL KLYTGEACRT GDR
Target Information
Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO induces the final maturation of partially differentiated erythroid cells and promotes production of red cell–specific proteins such as hemoglobin.
The EPO receptor (EPOR) is highly expressed on precursor cells, with expression decreasing during maturation.
Hepatocytes are the main source of EPO in the fetus, while interstitial kidney cells become the primary source after birth. EPO expression increases under hypoxic conditions, and low expression levels are also detected in lung and brain tissues.
Recent studies suggest EPO may protect neuronal tissue and aid in repair following damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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