Thermo Fisher Scientific FLT3/CD135 Polyclonal Antibody
FLT3/CD135 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ELISA, Immunoprecipitation에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제되었습니다. 연구용으로 세포 신호전달 및 백혈병 관련 연구에 활용됩니다.
- 카탈로그번호
- FLT3-301AP
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 900–950 on human Receptor-type tyrosine-protein kinase FLT3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FLT3 (Fms-like tyrosine kinase 3) is a receptor tyrosine kinase belonging to the growth factor receptor family. Upon binding of its ligand, FLT3 undergoes homodimerization and autophosphorylation, activating downstream signaling pathways that regulate apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Constitutive activation of FLT3 due to mutations is associated with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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