Thermo Fisher Scientific COPS6 Polyclonal Antibody
Thermo Fisher Scientific의 COPS6 Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 항체로, Western blot에 최적화되어 있습니다. COP9 시그널로솜 복합체 연구에 적합하며, 세포 주기 조절 및 단백질 상호작용 분석에 활용됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA544972
- 판매단위
- pk
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Thermo Fisher Scientific COPS6 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human COPS6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607106 |
Product Specific Information
- Peptide sequence: DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV
- Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 93%
Target Information
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome are similar to those of the 19S regulatory particle of the 26S proteasome. COP9 signalosome interacts with SCF-type E3 ubiquitin ligases and acts as a positive regulator of these ligases. This protein belongs to the translation initiation factor 3 superfamily and is involved in cell cycle regulation. It is also likely to serve as a cellular cofactor for the HIV-1 accessory gene product Vpr.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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