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Thermo Fisher Scientific GCLM Polyclonal Antibody
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GCLM 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot 및 Immunocytochemistry에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 항산화 관련 연구 및 GSH 합성 효소 분석에 적합합니다.
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마지막 업데이트 2025. 08. 03. 오후 01:36
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Thermo Fisher Scientific PA529908 GCLM Polyclonal Antibody 100 ul pk판매 단위 pk ·
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650,100원VAT 포함 715,110원
Thermo Fisher Scientific · Thermo Fisher Scientific GCLM Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:10,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–261 of Human GCLM |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547382 |
Product Specific Information
- Recommended positive controls: HeLa, A431, mouse liver, rat liver, rat kidney.
- Predicted reactivity: Mouse (97%), Rat (96%), Bovine (96%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate-limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis.
GSH acts as a vital intra- and extracellular antioxidant in mammalian cells.
Gamma-GCS is a heterodimer composed of a heavy catalytic subunit and a light regulatory subunit, responsive to inflammation, phenolic antioxidants, heat shock, oxidants, and cytokines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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