
Thermo Fisher Scientific RHOG Monoclonal Antibody (2E6)
RHOG 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot과 ELISA에 적합합니다. GST 태그가 포함된 부분 재조합 단백질을 면역원으로 사용하며, PBS(pH 7.4) 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E6 |
| Immunogen | RHOG (NP_001656, 94 a.a. ~191 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
RHKWHPEVCH HCPDVPILLV GTKKDLRAQP DTLRRLKEQG QAPITPQQGQ ALAKQIHAVR YLECSALQQD GVKEVFAEAV RAVLNPTPIK RGRSCILL
Target Information
The Ras p21 family of guanine nucleotide proteins has been widely studied for its role in signal transduction pathways and frequent mutations in human malignancies. Ras proteins (H-, K-, and N-Ras p21) belong to a larger superfamily of related proteins. Six members of this family—Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A, and Ral B—share approximately 50% amino acid homology with Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7, and 8) are about 30% homologous to Ras and are expressed in various cell types. Both Ras p21 and Rho p21, along with other Ras superfamily members, contain a carboxy-terminal CAAX sequence (C: cysteine; A: aliphatic amino acid; X: any amino acid), which is essential for correct localization and function in Ras proteins.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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