Thermo Fisher Scientific FTO Polyclonal Antibody
FTO 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 사용 가능하며, 인간·생쥐·닭 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | Assay-Dependent | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a C-terminal portion within residues 400–505 of the human protein (Swiss-Prot# Q9C0B1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/tris phosphate, pH 7–8 |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2247041 |
Product Specific Information
Suggested positive control: human brain lysate, human brain protein.
Target Information
FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)- and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicate that both 2-oxoglutarate and iron are important for FTO function. Though not much is yet known about FTO, it is thought that the protein may modify the activity of genes involved in metabolism and fat storage, influencing a person’s risk of obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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