Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI1D11), TrueMAB
인체 DOK7 단백질을 표적으로 하는 마우스 단일클론 항체로, WB, IHC(P), Flow Cytometry에 사용 가능. 고순도 액상 형태로 제공되며, 신경근 시냅스 형성 관련 연구에 적합. -20°C 보관, 동결·해동 반복 피할 것.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D11 |
| Immunogen | Full length human recombinant protein of human DOK7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase (MuSK), which is required for postsynaptic differentiation and clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of MuSK. Mutations in this gene cause familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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