Thermo Fisher Scientific DUSP7 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DUSP7 (AAH19107.1, 1 a.a. approximately 320 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DUSP7,uniProtId:Q16829-1,ncbiNodeId:9606,antigenRange:1-419,antigenLength:419,antigenImageFileName:H00001849-B01P_DUSP7_Q16829-1_House_mouse.svg,antigenImageFileNamePDP:H00001849-B01P_DUSP7_Q16829-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MLRRLRKGNL PIRSIIPNHA DKERFATRCK AATVLLYDEA TAEWQPEPGA PASVLGLLLQ KLRDDGCQAY YLQGGFNKFQ TEYSEHCETN VDSSSSPSSS PPTSVLGLGG LRISSDCSDG ESDRELPSSA TESDGSPVPS SQPAFPVQIL PYLYLGCAKD STNLDVLGKY GIKYILNVTP NLPNAFEHGG EFTYKQIPIS DHWSQNLSQF FPEAISFIDE ARSKKCGVLV HCLAGISRSV TVTVAYLMQK MNLSLNDAYD FVKRKKSNIS PNFNFMGQLL DFERTLGLSS PCDNHASSEQ LYFSTPTNHN LFPLNTLEST

Target Information

DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.