Thermo Fisher Scientific EPS15R Polyclonal Antibody
Rabbit polyclonal antibody targeting human EPS15R protein. Validated for WB and IHC applications. High antigen specificity with 94% sequence identity to mouse and rat orthologs. Supplied as liquid, unconjugated form with 0.6 mg/mL concentration. Suitab...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EPS15R. Recombinant protein control fragment (Product # RP-92469) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641073 |
Product Specific Information
Immunogen sequence:
KQDAQDRLDE MDQQKAKLRD MLSDVRQKCQ DETQMISSLK TQIQSQESDL KSQEDDLNRA KSELNRLQQE ETQLEQSIQA GRVQLETIIK SLKSTQDEIN QARSKLSQ
Sequence identity:
- Mouse: 94%
- Rat: 94%
Target Information
EPS15R is a constitutive component of clathrin-coated pits required for receptor-mediated endocytosis. It is involved in the endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Internalization of ITGB1 as DAB2-dependent cargo, but not TFR, requires association with DAB2.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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