Thermo Fisher Scientific Mouse TSLP Synthetic Peptide
마우스 TSLP 중심부 20개 아미노산 서열로 구성된 합성 펩타이드입니다. PA5-20321 항체의 블로킹 펩타이드로 사용 가능하며, 순도 높은 PBS 용액 형태로 제공됩니다. 마우스 TSLP 관련 연구용으로 적합하며, -20°C에서 보관합니다.
- 카탈로그번호
- PEP0441
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 20 amino acids near the center of mouse TSLP.
PEP-0441 can be used as a blocking peptide with polyclonal antibody PA5-20321.
Target Information
TSLP is a 159 amino acid four-helix bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain.
It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c(+) dendritic cells, naive CD4(+) and CD8(+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation.
TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4(+) T cell homeostasis.
It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis.
It is expressed in heart, liver, and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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