
Thermo Fisher Scientific AFP Monoclonal Antibody (OTI3B5), TrueMAB
인간 AFP 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot 및 유세포분석에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로 간암 및 생식세포종 관련 AFP 검출에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B5 |
| Immunogen | Full length human recombinant AFP protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal life. In adults, AFP expression is often associated with hepatoma or teratoma. Hereditary persistence of AFP may also occur in individuals without pathology. AFP is considered the fetal counterpart of serum albumin, with both genes located tandemly on chromosome 4. AFP exists in monomeric, dimeric, and trimeric forms and can bind copper, nickel, fatty acids, and bilirubin. AFP levels in amniotic fluid are used to screen for spina bifida and anencephaly. Elevated serum AFP levels are observed in hepatocellular carcinoma, teratoblastoma, colorectal, pancreatic cancers, and germ cell neoplasms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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