Thermo Fisher Scientific AFP Monoclonal Antibody (OTI3B5), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Target Information

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal life. In adults, AFP expression is often associated with hepatoma or teratoma. Hereditary persistence of AFP may also occur in individuals without pathology. AFP is considered the fetal counterpart of serum albumin, with both genes located tandemly on chromosome 4. AFP exists in monomeric, dimeric, and trimeric forms and can bind copper, nickel, fatty acids, and bilirubin. AFP levels in amniotic fluid are used to screen for spina bifida and anencephaly. Elevated serum AFP levels are observed in hepatocellular carcinoma, teratoblastoma, colorectal, pancreatic cancers, and germ cell neoplasms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.