Thermo Fisher Scientific GBA3 Monoclonal Antibody (OTI1F1), TrueMAB
인간 GBA3 단백질을 인식하는 Mouse monoclonal 항체로, WB, IHC(P), Flow Cytometry에 적합합니다. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–150 and 370–469 of human GBA3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside. This suggests that it may be involved in detoxification of plant glycosides.
GBA3 also exhibits significant neutral glycosylceramidase activity (EC 3.2.1.62), indicating a potential role in a nonlysosomal catabolic pathway of glucosylceramide metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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