Thermo Fisher Scientific FAM3B Polyclonal Antibody
FAM3B 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며, PBS 버퍼와 0.09% sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human FAM3B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608420 |
Product Specific Information
- Peptide sequence:
HWTPCPSDTY AYRLLSGGGR SKYAKICFED NLLMGEQLGN VARGINIAIV - Sequence homology:
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 86%
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. It is expressed at high levels in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine. FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit insulin secretion from beta-cells, possibly contributing to pancreatic activity regulation. Human FAM3B shares 78% sequence identity with its mouse counterpart, indicating a conserved function across species. Three isoforms (A, B, and C) exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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