Thermo Fisher Scientific RBBP6 Polyclonal Antibody
인간 RBBP6 단백질의 N-말단 펩타이드(aa 13-62)를 항원으로 제작된 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot에 1 µg/mL 농도로 사용 가능하며, 높은 종 간 서열 보존도를 보입니다. 액상 형태, 0.5 mg/mL 농도, -20°C 보관 조건.
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Applications
- Western Blot (WB): Tested dilution 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human RBBP6 (aa 13–62) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607044 |
Product Specific Information
Peptide sequence:
NYDTVTFDGL HISLCDLKKQ IMGREKLKAA DCDLQITNAQ TKEEYTDDNA
Sequence homology:
Cow: 100%
Dog: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Pig: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 93%
Target Information
This gene encodes a cilia-associated protein belonging to the kinesin family. It plays a role in the sonic hedgehog (SHH) signaling pathway by regulating GLI transcription factors.
- Functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand.
- Acts as a positive regulator by preventing the processing of GLI3 into its repressor form.
Mutations in this gene have been associated with various ciliopathies.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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