Thermo Fisher Scientific BMP-4 Monoclonal Antibody (10F4B4)
인간 BMP4 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 ELISA에 적합하며, 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10F4B4 |
| Immunogen | Purified recombinant fragment of human BMP4 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10982380 |
Product Specific Information
MA5-15572 targets BMP4 in indirect ELISA and WB applications and shows reactivity with human samples. The immunogen is a purified recombinant fragment of human BMP4 expressed in E. coli.
MA5-15572 detects BMP4, which has a predicted molecular weight of approximately 64 kDa.
Target Information
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family, part of the transforming growth factor-beta (TGF-β) superfamily. These proteins are growth and differentiation factors originally identified by their ability to induce endochondral osteogenesis in vivo.
BMP4 plays a key role in the onset of endochondral bone formation in humans. Reduced expression is associated with several bone-related diseases, including Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5′ untranslated region has been described, producing three variants encoding an identical protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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