Thermo Fisher Scientific SAPAP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SAPAP2. Recombinant protein control fragment (Product #RP-93954). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SAPAP2,uniProtId:Q9P1A6-1,ncbiNodeId:9606,antigenRange:273-372,antigenLength:1054,antigenImageFileName:PA5-56438_SAPAP2_Q9P1A6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56438_SAPAP2_Q9P1A6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646941

Product Specific Information

Immunogen sequence: HSKRSKSKER KPEGKPRPGM SSWWSSDDNL DSDSTYRTPS VLNRHHLGPV AHCYPDALQS PFGDLSLKTS KSNNDVKCSA CEGLALTPDA KYLKRSSWST

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.

Target Information

SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.