
Thermo Fisher Scientific Ocrelizumab Humanized Recombinant Human Monoclonal Antibody
Ocrelizumab는 인간화 재조합 단일클론 항체로, CD20을 표적으로 하는 B세포 선택적 결합 특성을 가집니다. 다발성경화증 연구용으로 적합하며, 높은 순도와 낮은 엔도톡신 수준을 유지합니다. 연구용으로만 사용 가능합니다.
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Applications
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1 |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human MS4A1/CD20 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2910972 |
Product Specific Information
- Endotoxin level: < 0.01 EU/µg (LAL method)
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with relapsing or primary progressive forms of multiple sclerosis. It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B lymphocytes expressing the CD20 antigen. As a humanized molecule, ocrelizumab is expected to be less immunogenic with repeated infusions, improving the benefit-to-risk profile for patients with relapsing or progressive forms of MS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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