Thermo Fisher Scientific P2X6 Polyclonal Antibody
P2X6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, Flow Cytometry에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within rat P2rx6 aa 340–389 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2901068 |
Product Specific Information
Positive controls: Jurkat cell lysate, K562 cell lysate, rat skeletal muscle tissue, rat brain tissue, mouse skeletal muscle tissue, mouse heart tissue, SH-SY5Y.
Target Information
Gene: P2rx6
P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is composed of a trimer of subunits (P2X1–7), all sharing two transmembrane domains. The protein belongs to the family of P2X receptors, which are ATP-gated ion channels mediating rapid and selective cation permeability.
P2rx6 is predominantly expressed in skeletal muscle and regulated by p53. The encoded protein associates with VE-cadherin at adherens junctions of human umbilical vein endothelial cells. Alternative splicing generates multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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