Thermo Fisher Scientific Olamkicept Humanized Recombinant Human Monoclonal Antibody
IL-6 trans-signaling 억제용 인간화 재조합 단일클론 항체. ELISA 등 연구용으로 적합하며, CHO 세포에서 발현된 IgG1 kappa 형태. sIL-6R 결합을 통해 염증 신호 억제. 단백질 A/G로 정제된 무보존액 액상 항체.
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Thermo Fisher Scientific Olamkicept Humanized Recombinant Human Monoclonal Antibody
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Recombinant Human IL6 and CD126/IL6R/IL-6RA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Olamkicept acts as an IL-6 trans-signaling inhibitor by selectively binding to the soluble IL-6 receptor (sIL-6R), preventing the formation of the IL-6/sIL-6R complex and subsequent activation of the gp130 receptor, thereby inhibiting downstream inflammatory signaling pathways.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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