Thermo Fisher Scientific Pan-HLA-II (DP, DQ, DR) Monoclonal Antibody (HLA-Pan/6663)
인간 HLA-DR, DQ, DP 항원을 인식하는 Pan-HLA-II 단클론 항체로, 면역조직화학(IHC) 및 유세포분석(Flow Cytometry)에 적합합니다. Mouse IgG1, kappa 아이소타입이며, Protein A/G 정제 및 PBS 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Flow Cytometry (Flow)
- 1–2 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HLA-Pan/6663 |
| Immunogen | Priess human B cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen-presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells, and activated T lymphocytes.
Three loci—DR, DQ, and DP—encode the major expressed products of the human class II region.
Human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells, playing a critical role in initiating the immune response.
HLA and MHC antibodies are essential in immunopeptidomics, enabling identification and characterization of neoantigens via high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MSM3-6663-P0_HLA-DRDPDQ_P01911-1_House_mouse.svg, MSM3-6663-P0_HLA-DRDPDQ_P01911-1_House_mouse_PDP.jpeg, MSM3-6663-P0_HLA-DRDPDQ_P01920-1_House_mouse.svg, MSM3-6663-P0_HLA-DRDPDQ_P01920-1_House_mouse_PDP.jpeg, MSM3-6663-P0_HLA-DRDPDQ_P04440-1_House_mouse.svg, MSM3-6663-P0_HLA-DRDPDQ_P04440-1_House_mouse_PDP.jpeg)
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