Thermo Fisher Scientific MMP7 Monoclonal Antibody (OTI4H8), TrueMAB
Human MMP7 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. TrueMAB 포맷으로 높은 특이성과 재현성을 제공하며, 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 95–267 of human MMP7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes including arthritis and metastasis.
Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin, and casein, and differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
It is involved in wound healing, and studies in mice suggest that it regulates defensin activity in the intestinal mucosa.
The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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