ELK Biotechnology KCNS3 rabbit pAb

KCNS3 rabbit pAb

공급업체: ELK Biotechnology
제품명: KCNS3 rabbit pAb

제품 개요

KCNS3 단백질을 인식하는 토끼 유래 폴리클로날 항체로, 전압 개폐성 칼륨 채널 연구에 적합합니다. 인간 및 생쥐 시료에서 반응하며, 세포막에 존재하는 다중 통과 단백질 검출에 사용할 수 있습니다.

응용 분야

• WB (Western Blot)
• ELISA

권장 희석 배수

• WB: 1:500–1:2000
• ELISA: 1:5000–1:20000

제품 사양

세포 내 위치

Cell membrane; Multi-pass membrane protein. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328).

배경 정보

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials.
The alpha subunits are of two types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits.
The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins.
This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been identified.