ELK Biotechnology KCNE3 rabbit pAb
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| Product name: | KCNE3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 11kD |
| GeneID（Human）: | 10008 |
| Human Swiss-Prot No: | Q9Y6H6 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Perikaryon . Cell projection, dendrite . Membrane raft . Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal neurons. . |
| Background: | potassium voltage-gated channel subfamily E regulatory subunit 3(KCNE3) Homo sapiens Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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