ELK Biotechnology KCNB2 rabbit pAb
KCNB2 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 사람, 쥐, 생쥐 시료에 반응하며, 세포막 및 수상돌기에서 발현을 탐지할 수 있습니다. 장기 보관은 -20°C에서 1년 가능합니다.
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KCNB2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | KCNB2 rabbit pAb |
| Applications | WB, ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 170–250) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100 kDa |
| GeneID (Human) | 9312 |
| Human Swiss-Prot No. | Q92953 |
| Species Reactivity | Human, Rat, Mouse |
| Cellular Localization | Cell membrane; Multi-pass membrane protein; Perikaryon; Cell projection (dendrite). Localized uniformly throughout cell bodies and dendrites. Colocalizes with KCNB1 in high-density somatodendritic clusters on cortical pyramidal neurons. |
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes — shaker, shaw, shab, and shal — have been identified in Drosophila, and each has human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.
(Provided by RefSeq, Jul 2008)
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