
ELK Biotechnology PI3R6 rabbit pAb
PI3R6 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 사람, 생쥐, 랫트 시료에서 반응하며 세포막 및 세포질에 위치한 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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PI3R6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–1:2000, ELISA 1:5000–1:20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 280–360) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 82 kD |
| Gene ID (Human) | 146850 |
| Human Swiss-Prot No. | Q5UE93 |
| Cellular Localization | Cytoplasm, Cell membrane; Peripheral membrane protein. Translocated to the plasma membrane in a Ras-dependent manner. |
| Species Reactivity | Human; Rat; Mouse |
Background
Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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