ELK Biotechnology NRX1B rabbit pAb
NRX1B rabbit pAb는 인간, 생쥐, 랫트에 반응하는 다클론 항체로 WB 및 ELISA에 적합합니다. 인간 단백질 유래 펩타이드로 면역화되었으며, 세포 접합부 및 시냅스에 위치한 단백질을 검출합니다. 고특이성 IgG 항체로 -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology NRX1B rabbit pAb
NRX1B rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NRX1B rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 260–340) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48 kD |
| GeneID (Human) | 9378 |
| Human Swiss-Prot No | P58400 |
| Cellular Localization | Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
A number of isoforms are produced by alternative promoter usage, including the alpha-type (AC Q9ULB1) and beta-type (AC P58400) isoforms, which differ in their N-terminus. Additional isoforms may be produced by alternative splicing.
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. Plays a role in the formation or maintenance of synaptic junctions and may mediate intracellular signaling.
Post-translational modifications (PTM):
- Highly O-glycosylated and minor N-glycosylated
- N- and O-glycosylated
Similarity:
- Belongs to the neurexin family
- Contains 1 laminin G-like domain
- Contains 3 EGF-like domains
- Contains 6 laminin G-like domains
Subunit interactions:
- The cytoplasmic C-terminal region binds to CASK, CASKIN1, and APBA1
- Laminin G-like domain 2 binds to NXPH1
- Specific isoforms bind to alpha-dystroglycan and alpha-latrotoxin
- Isoforms Beta 4b bind neuroligins NLGN1, NLGN2, NLGN3, alpha-dystroglycan, and alpha-latrotoxin
Tissue specificity: Heart and brain
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.