ELK Biotechnology ULA1 rabbit pAb
ULA1 rabbit polyclonal antibody for WB and ELISA; targets human ULA1 protein involved in cell cycle and Alzheimer’s disease; high specificity and stability; suitable for human, rat, and mouse samples.
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ELK Biotechnology ULA1 rabbit pAb
제품 개요
ULA1 rabbit polyclonal antibody는 인간 ULA1 단백질을 인식하며, 세포막에 위치하고 APP와 공위치하는 단백질을 검출하는 데 사용됩니다. 이 단백질은 베타-아밀로이드 전구체 단백질과 결합하며, 알츠하이머병의 병태생리와 세포 주기 조절에 관여합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | ULA1 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein, AA range: 390–470 |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 58 kD |
| GeneID (Human) | 8883 |
| Human Swiss-Prot No. | Q13564 |
| Cellular Localization | Cell membrane; colocalizes with APP in lipid rafts |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer’s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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