ELK Biotechnology MYO3A rabbit pAb
MYO3A 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 인체 및 생쥐 반응성. 세포질 및 세포골격에 주로 발현되며, 청각 관련 연구에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology MYO3A rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MYO3A rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 180–260) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 177 kD |
| GeneID (Human) | 53904 |
| Human Swiss-Prot No | Q8NEV4 |
| Cellular Localization | Cytoplasm, cytoskeleton, cell projection (filopodium tip, stereocilium). Increased localization at filopodium tip in presence of MORN4. |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins categorized into conventional (class II) and unconventional (classes I and III–XV) types based on their variable C-terminal cargo-binding domains.
Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved motor domains and are expressed in photoreceptors.
This protein plays an important role in human hearing. Loss-of-function mutations in the encoded protein are associated with nonsyndromic progressive hearing loss. Expression is highly restricted, with strongest expression in retina and cochlea.
(Information provided by RefSeq, Jul 2008)
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