Thermo Fisher Scientific GLRX2 Polyclonal Antibody
GLRX2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 인간·생쥐·랫드 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific GLRX2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human GLRX2 (Accession Q9NS18), amino acid residues Y113–F163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899926 |
Product Specific Information
Antibody detects endogenous levels of total GLRX2.
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs are part of the glutaredoxin system comprising NADPH, GSH, and glutathione reductase, transferring electrons from NADPH to glutaredoxins via GSH.
Originally discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved across species. The 12-kDa dithiol protein plays a role in reducing mixed disulfides in cells under oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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