ELK Biotechnology INVS rabbit pAb
INVS 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 사람과 생쥐 시료에 반응하며, 세포질 및 세포골격 관련 단백질 연구에 유용합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
INVS rabbit pAb
제품 개요
INVS 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. 사람 및 생쥐 시료에서 사용 가능하며, 세포질 및 세포골격 관련 단백질의 발현 및 위치 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 117 kD |
| Gene ID (Human) | 27130 |
| Human Swiss-Prot No | Q9Y283 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Cytoplasm; Cytoplasm, cytoskeleton; Cytoplasm, cytoskeleton, spindle; Membrane (Peripheral membrane protein); Nucleus; Cell projection, cilium. Associates with several components of the cytoskeleton including ciliary, random and polarized microtubules. During mitosis, it is recruited to mitotic spindle. Frequently membrane-associated, membrane localization is dependent upon cell-cell contacts and is redistributed when cell adhesion is disrupted after incubation of the cell monolayer with low-calcium/EGTA medium. |
Background
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. (provided by RefSeq, May 2012)
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