ELK Biotechnology IMA1 rabbit pAb
IMA1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 인간, 랫, 마우스 시료에 반응하며 세포질과 핵에 위치한 단백질 검출에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology IMA1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | IMA1 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–1:2000, ELISA 1:5000–1:20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 59 kD |
| Gene ID (Human) | 3836 |
| Human Swiss-Prot No. | P52294 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Rat, Mouse |
Background
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60–100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
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