Thermo Fisher Scientific pan Cytokeratin Polyclonal Antibody
인간, 마우스, 돼지, 랫트에 반응하는 Rabbit Polyclonal pan Cytokeratin 항체로 다양한 IHC, WB, ICC, Flow, ELISA 적용 가능. KLH 결합 합성 펩타이드로부터 유래, Protein A 정제, 고농도(1 mg/mL) 액상 형태. 세포골격 연구용으로 적합.
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Thermo Fisher Scientific pan Cytokeratin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human pan cytokeratin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins are keratin-containing intermediate filament proteins found within the cytoskeleton of epithelial cells. They are encoded by a family of 30 genes, with 20 being epithelial-specific and 10 trichocyte-specific. These filaments form a complex network extending from the nuclear surface to the cell membrane, interacting with desmosomes and hemidesmosomes to support cell-cell adhesion and connection to underlying connective tissue. Cytokeratin networks not only provide structural support but also participate in dynamic cellular processes such as mitosis, movement, and differentiation through phosphorylation-mediated depolymerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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