Thermo Fisher Scientific CD44v4 (Marker of Tumor Metastasis) Polyclonal Antibody
CD44v4 domain을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응. 종양 전이 마커 연구에 적합하며, IHC(P) 및 IHC(PFA) 실험에서 사용 가능. Protein A 정제 및 PBS/BSA 버퍼 내 액상 형태로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific CD44v4 (Marker of Tumor Metastasis) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to the v4 domain of human CD44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration. It also participates in lymphocyte activation, recirculation, and homing. CD44 expression may be up-regulated in some carcinomas, potentially related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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